Dentifrice



Patented Oct. 18, 1927.

UNITED STATES ROY H. mm, PITTSBURGH, PENNSYLVANIA.

DENTII'BICE.

Io Drawing.

This invention relates to a dentifrice and constitutes a continuation inpart of apphcation Serial No. 109,164, filed May 14, 1926.

is to increase the antiseptic action of. the,

dentifrices of the above noted inventions, without detractin from theircleansing properties, and wit out imparting an in ur1 ous effect orunpleasant odor to them. In such applications the dentifrices compriseas their chief active ingredient, or in- 90 dients one or more halidesof aliphatic 5% ns. halides of aliphatic hydrocar ns, carbontetrachloride (tetrachlor methane) and eth l iodide may be particularlynoted. ather halides of methane itself may be used instead of the carbontetrachloride, and halides of the other members of the series may alsobe substituted therefor. Of the other halides of methane, di-iodomethane (CH,I,) may be used in the composition if so desired. Of thetrihalides of methane, chloroform 83515301,) may be used, but bromoformr and lodoform (OHL) as commercially available, have too penetra andunpleasantly pungent an odor to ren er their use in a dentifricedesirable. Although chloroform may be used, its high rate of evaporationrenders it a less deslrable ingredient than carbon tetrachloride or ethl iodide.

(If the tetra halides of methane, tetrachlor methane has been givenabove as one of the substances of greatest suitabili 4 because of itshysical properties and re y availability. 8f the ot er tetrahalides,carbon tetrabromide (C'Br and carbon tetraiodide (CL), the tetraiodidepossesses and emrable in a dentifrice.

Of the halides of the higher members of the parafiin series variousmembers may be advantageously utilized. 7

In regard to any of these substances it may be stated as a general1principle that the more desirable are those aving a boilthe mostsuitable exam les of such P ical roperties which render its use posslle- Application fled October 1a, 1926. swarm. 141,421.-

ing point between twenty-five de grade and one hundre and fi y degreescentigrade, To express the matter difierently, the more desirable arethose which are liquids at room temperature and atmosphenc pressure. Thecompounds having a boiling point lower than twentg-fiw degreescentigrade tend to evaporate cm or se arate in the composition, whilethose which are solid at room temperature and atmospheric pressure aretoo inactive to impart the desired qualities to the dentifrice.

The halogen substitution products of several of the ethylene series ofhydrocarbons may also be used in the dentifrice. Of these the mostsuitable members are ethylene chloride (C H,Cl,) and methylene chloride(CH cl A number of the halides of the acetylene series also possessdesirable characteristics, for example, the monohalides of propargyl.

It has been found that the elemental iodine increases the antisepticproperties of the dentrifice, without in any degree detracting from thecleansin actlon of the organic halide in which it 1s dissolved. Theiodine is readil soluble in any of the organic halides glven, itssolubility in a few of them being as follows:

Solubility of iodine ees centi- It should be understood that a number ofOrganic halide. therein Carbon tetrachloride 3 Chloroform 1.75 Ethyliodide In excess of 10 'tard evaporation of the solution or so A.satisfactory conilpoaition may com rise the iodine solution an whitemineral o in substantially'equal pro rtions. In this connection methyliodi e, whichhas a boiling Y point of only forty-three degreescentigrade,

be satlsfactoril used as the orgamc hahde serving as a so vent for theiodine, for the reason that in this connection there is less opportunifor evaporation of the active ingredient o the com 'tion.

For use in a dentifrice, the iodine is first dissolved in the organichalide. This liquid solution is then mixed with white mineral oil. Thismixture may then be added to the various other constituents of thedentifrice, such as calcium carbonate, magnesium carbonate, g1 cerine,soap solution, flavoring matter an water.

A dentifrice comprising the above noted, or similar, constituentscontains neither gitty material which tends to wear down e teeth nor anyactive'agent ca able of exerting a solvent action thereon. t is capableof removing the mucin film from the teeth, thus a thoroeugh cleansingthereof; an serves asan cient germieide, and as a stimulant of the gumsand other tissues of the oralcavity.

YVhzt llclailln is:

enta re aration comprising a halide of an alip atii: hydrocarbon, andelementaliodine dissolved in said organic halidX d l v v 2. enta prearation com nsmg' eth l iodide, and eleriiental iodin e dissolve dtherein;

3. A dentifrice comprising a halide of an aliphatic hydrocarbon avmg'aboi int between the limits of twenty-five a eg ees centigrade and onehundred d centigrade, elemental iodine, filling material,

and alwlliite rfnineral oiL h 1 odld 4. enti rice com rising at i e,elemental iodine disso lved therei n, filling material, and a whitemineral oil.

In witnes whereof, I hereunto set my hand.

ROY H. BBOWNLEE.

